Compounded Amlexanox
Compare quotes for compounded Amlexanox, see whether a prescription is needed, what affects price, how fast quotes come back, and what happens after you submit.
About Amlexanox
Amlexanox is an anti-inflammatory medication used to treat recurrent aphthous ulcers (canker sores) and oral lichen planus. The FDA-approved commercial product — Aphthasol 5% oral paste — was discontinued in the U.S., leaving compounding pharmacies as the only legal source for patients who relied on it. Licensed 503A compounding pharmacies prepare amlexanox 5% oral paste and mouth rinses by prescription; there is no generic alternative.
Why compounding is the only source of amlexanox
Aphthasol (amlexanox 5% oral paste) was the only FDA-approved product containing amlexanox and was discontinued in the United States. No generic version was ever approved. For patients whose providers want to prescribe amlexanox for recurrent canker sores, oral lichen planus, or Behçet's-related oral ulcers, a compounding pharmacy is the only legal domestic source.
The active ingredient is still manufactured as a pharmaceutical-grade API and can be compounded under Section 503A rules with a valid prescription from a licensed U.S. dentist, oral surgeon, or physician.
Available formulations
Most compounding pharmacies prepare amlexanox as a 5% oral paste (matching the original Aphthasol strength) or as a 2% mouth rinse for patients with widespread oral involvement. Custom strengths between 2% and 5%, and combination formulations with anesthetics like lidocaine, are available on request.
Ask your prescriber whether paste or rinse is more appropriate for your ulcer pattern — paste works well for one or two discrete ulcers, while rinse is better for multiple simultaneous lesions.
How amlexanox is used
The 5% paste is typically applied four times daily — after each meal and at bedtime — directly on each ulcer for four to six weeks, or until the ulcer heals. Most patients notice pain reduction within two to three days and full ulcer healing within seven to fourteen days per outbreak.
The 2% rinse is swished for 30 seconds, two to four times daily, and suits patients with multiple ulcers better than the paste. Avoid eating or drinking for at least 30 minutes after either formulation.
Typical compounded amlexanox pricing
Because amlexanox API is relatively expensive and the compound is specialty-tier, most pharmacies price a 5-gram tube of 5% oral paste in the $60–$150 range depending on volume, shipping, and strength. Prices can vary two to three times between pharmacies.
Getting quotes from multiple licensed compounding pharmacies before filling typically saves 20–40%, which matters over a multi-month treatment course.
Key Questions Before You Request Quotes
Can I get Amlexanox compounded?
Possibly. A licensed prescriber has to decide whether Amlexanox is appropriate, and a licensed compounding pharmacy has to confirm it can legally prepare the requested strength, form, and quantity.
Is a prescription needed?
Yes. Patient-specific 503A compounding is based on a valid prescription order or prescriber notation for an identified patient.
What affects price?
Strength, dosage form, quantity, ingredient sourcing, sterile versus non-sterile preparation, shipping requirements, and each pharmacy's workflow can all change the final quote.
How fast can I get quotes?
For routable requests, Compounding Finder typically returns quote options by email within 1-2 business days after you submit the request details.
What happens after I submit?
We review the request, route it to eligible licensed pharmacies, collect available options, and email you the quoted choices. You decide whether to move forward with a pharmacy.
Source notes: FDA explains that compounded drugs are not FDA-approved finished products and describes 503A compounding around patient-specific prescriptions. See Compounding and the FDA and Section 503A.
Typical Amlexanox Pricing
Prices vary by dosage, formulation, quantity, and pharmacy. The range above reflects listings currently tracked by Compounding Finder and is not a guaranteed quote. Submit a request below to get a personalized quote for your specific needs.
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Amlexanox by State
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Why Compare Amlexanox Prices?
Compounded medication prices vary significantly between pharmacies — sometimes by 300% or more for the exact same drug, strength, and formulation. Factors that affect pricing include the pharmacy’s location, their ingredient sourcing, and compounding volume.
By comparing quotes from multiple licensed pharmacies, you can find the best combination of price, quality, and convenience without spending hours making phone calls.
Frequently Asked Questions
Is amlexanox still available in the U.S.?
Yes, through compounding pharmacies. The branded Aphthasol 5% oral paste was discontinued commercially, but licensed 503A compounding pharmacies can prepare amlexanox on a per-prescription basis. There is no generic FDA-approved version.
Do I need a prescription for compounded amlexanox?
Yes. Amlexanox is a prescription-only medication, and compounding pharmacies cannot dispense it without a valid prescription from a licensed U.S. healthcare provider — typically a dentist, oral surgeon, or physician treating recurrent oral ulcers.
How much does compounded amlexanox cost?
Most compounded 5% oral paste is priced in the $60–$150 range for a 5-gram tube. Pricing varies by pharmacy, volume, and shipping region. Because amlexanox is a specialty compound, it's worth requesting quotes from multiple pharmacies before filling.
How long does amlexanox take to work?
Most patients see pain reduction within two to three days of starting treatment, with full ulcer healing typically within seven to fourteen days per outbreak. The paste is applied four times daily — after meals and at bedtime — for best results.
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